{"id":5774,"date":"2023-01-24T14:50:45","date_gmt":"2023-01-24T14:50:45","guid":{"rendered":"https:\/\/www.gradiant.com\/?post_type=success-stories&p=5774"},"modified":"2025-05-16T08:13:13","modified_gmt":"2025-05-16T12:13:13","slug":"pharmaceuticals-minimum-liquid-discharge","status":"publish","type":"success-stories","link":"https:\/\/www.gradiant.com\/de\/success-stories\/pharmaceuticals-minimum-liquid-discharge\/","title":{"rendered":"Pharmazeutika - Mindestabgabe von Fl\u00fcssigkeiten"},"content":{"rendered":"
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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"pharma\"\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t
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Pharmazeutika<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t<\/path><\/path><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\tpdf herunterladen<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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MINIMAL LIQUID DISCHARGE BEI EXTREM BEGRENZTER STELLFL\u00c4CHE<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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Only Gradiant was able to provide a Minimum Liquid Discharge solution to meet GSK\u2019s demanding performance specification within an extremely limited\nexisting footprint. Engineering a bespoke Carrier Gas Extraction design where others had failed.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Kurz & Knapp<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Standort<\/strong>: Singapur<\/p>

Endverbraucher<\/strong>: GlaxoSmithKline (GSK)<\/p>

L\u00f6sung<\/strong>: Minimal Liquid Discharge<\/p>

Industrie<\/strong>: Pharmazeutika<\/p>

Speisewasserquelle<\/strong>: Abw\u00e4sser aus der Arzneimittelproduktion<\/p>

Technologie<\/strong>: Tr\u00e4gergasextraktion (CGE), D\u00fcnnschichttrockner (ATFD)<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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System-Konfiguration:<\/strong>2 x 50 % CGE und 100 % ATFD<\/p>

Kapazit\u00e4t des Systems<\/strong>: 288 m\u00b3\/Tag<\/p>

Systemwiederherstellung<\/strong>: 98%<\/p>

Online Datum<\/strong>: Juni 2022<\/p>

Liefermodell<\/strong>: Design-Build (DB)<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Die Herausforderung<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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GlaxoSmithKline (GSK) ist ein weltweit t\u00e4tiges Pharma- und Biotechnologieunternehmen und ein f\u00fchrender Hersteller von Amoxicillin. In der Antibiotika-Produktionsanlage von GSK in Singapur fielen Abw\u00e4sser an, die organische L\u00f6sungsmittel und nicht zur\u00fcckgewonnene Amoxicillin-Produkte enthielten, was den Gesamtertrag der Produktion und die Abfallentsorgung beeintr\u00e4chtigte. Die prim\u00e4re Herausforderung bestand darin, eine kompakte Prozessl\u00f6sung zu finden, die hohe CSB-, TDS- und Chloridwerte im Abwasser nachhaltig behandeln konnte. Und das alles auf einer \u00e4u\u00dferst anspruchsvollen, begrenzten Fl\u00e4che, auf der Industriebrache zur Verf\u00fcgung stand.<\/p>

\u00a0<\/p>

GSK war nicht in der Lage, eine glaubw\u00fcrdige L\u00f6sung zu finden - da kam Gradiant ins Spiel.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Die L\u00f6sung<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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A bespoke version of our Carrier Gas Extraction technology \u2014 patented and award winning. The dedicated project delivery team deployed bench-scale lab testing to demonstrate proof of concept and the proven cost advantages of using CGE. Quantified results were complimented by in-house unique design innovation for the design-build project phase of this MLD facility \u2013 creating savings of 35% in CAPEX and 50% in OPEX relative to competitors.<\/p>\n

\u00a0<\/p>\n

Die Gradiant-Ingenieure konzipierten die CGE-Technologie als zwei 32-Meter-T\u00fcrme, um den sehr begrenzten Platzverh\u00e4ltnissen der bestehenden Anlage gerecht zu werden - ein bisher einmaliger Einsatz. Die CGE-Technologie hat anderen Kunden nachweislich geholfen, eine 20-fache Solekonzentration zu erreichen und in Kombination mit ATFD das Gesamtentsorgungsvolumen um \u00fcber 98 % zu reduzieren, w\u00e4hrend die CSB- und TDS-Konzentrationen im Abwasser gesenkt wurden. Das ZLD-Verfahrensschema f\u00fchrt die verbleibende konzentrierte Sole einem Agitated Thin Film Dryer zu, um einen Feststoffkuchen mit einer Reinheit von >80 % zu erzielen.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Die Vorteile<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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Die L\u00f6sung von Gradiant erwies sich als technisch und wirtschaftlich \u00fcberlegen, um die Solekonzentration und die minimale Fl\u00fcssigkeitsabgabe zu bew\u00e4ltigen - das Gesamtentsorgungsvolumen wurde um mehr als 98 % reduziert, w\u00e4hrend die CSB- und TDS-Konzentrationen im Abwasser gesenkt wurden. Durch die Implementierung der L\u00f6sung konnte sich unser Kunde GSK auf die weltweite Versorgung mit Amoxicillin und anderen wichtigen Medikamenten konzentrieren. Durch Einsparungen von bis zu 35 % und 50 % bei CAPEX und OPEX im Vergleich zu Technologien der Konkurrenz wurden die Erwartungen \u00fcbertroffen.<\/p>

\u00a0<\/p>

Nach der erfolgreichen Einf\u00fchrung des Projekts schafft Gradiant M\u00f6glichkeiten f\u00fcr andere pharmazeutische Markeneigent\u00fcmer, Nachhaltigkeit in ihren Betrieb zu bringen und ihre einzigartigen Produktionsherausforderungen zu l\u00f6sen. So wird sichergestellt, dass ihr Fokus weiterhin auf der Herstellung lebensrettender Medikamente und Heilmittel f\u00fcr die Weltbev\u00f6lkerung liegt.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Auswirkungsstatistiken<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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98% <\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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Verringerung des Entsorgungsvolumens<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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NULL <\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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Fl\u00fcssigkeitsabgabe<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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50%<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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Up to 50% Less Thermal Energy than Multi-Effect Evaporation and Distillation(MEE, MED) systems<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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50% <\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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Bis zu 50 % CAPEX- und OPEX-Einsparungen gegen\u00fcber den Wettbewerbern<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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50% <\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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More than 50% Energy Savings compared to Mechanical Vapor Compression (MVC) evaporation<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Zahlen und Bilder<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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GSK Process Flow Diagram<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"Diagramm\"\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Tr\u00e4gergas-Extraktion Prozessablaufschema<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"Diagramm\"\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Rechtlicher Hinweis<\/strong><\/p>

Dieses Dokument dient nur der allgemeinen Information. Es wird keinerlei Garantie oder Gew\u00e4hrleistung gegeben oder impliziert, und Gradiant ist nicht an die hierin enthaltenen Informationen gebunden und haftet nicht daf\u00fcr. Es liegt in der alleinigen Verantwortung des Kunden, festzustellen, ob die in diesem Dokument enthaltenen Informationen f\u00fcr die Verwendung durch den Kunden geeignet sind, einschlie\u00dflich und ohne Einschr\u00e4nkung der tats\u00e4chlichen Standort-, geografischen und Werksbedingungen, Spezifikationen, Anforderungen, Entsorgung, geltenden Gesetze und Vorschriften. Dieses Dokument ist geistiges Eigentum von Gradiant, einschlie\u00dflich, aber nicht beschr\u00e4nkt auf die in diesem Dokument enthaltenen Patente und Marken. Die Verteilung dieses Dokuments bedeutet nicht, dass das geistige Eigentum von Gradiant \u00fcbertragen wird.<\/p>

\u00a0<\/p>

Gradiant, das Gradiant Logo und alle mit \u2122 oder \u00ae gekennzeichneten Handels- und Dienstleistungsmarken sind, sofern nicht anders angegeben, Eigentum von Tochtergesellschaften der Gradiant Corporation. \u00a9 2024 Gradiant.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

Pharmaceuticals download pdf MINIMUM LIQUID DISCHARGE IN AN EXTREMELY LIMITED FOOTPRINT Only Gradiant was able to provide a Minimum Liquid Discharge solution to meet GSK\u2019s demanding performance specification within an extremely limited existing footprint. Engineering a bespoke Carrier Gas Extraction design where others had failed. Fast Facts Location: Singapore End User: GlaxoSmithKline (GSK) Solution: Minimum […]<\/p>\n","protected":false},"featured_media":9462,"template":"","class_list":["post-5774","success-stories","type-success-stories","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"\nPharmaceuticals \u2013 Minimum Liquid Discharge - Gradiant<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.gradiant.com\/de\/erfolgsgeschichten\/pharmaceuticals-minimum-liquid-discharge\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pharmaceuticals \u2013 Minimum Liquid Discharge - Gradiant\" \/>\n<meta property=\"og:description\" content=\"Pharmaceuticals download pdf MINIMUM LIQUID DISCHARGE IN AN EXTREMELY LIMITED FOOTPRINT Only Gradiant was able to provide a Minimum Liquid Discharge solution to meet GSK\u2019s demanding performance specification within an extremely limited existing footprint. Engineering a bespoke Carrier Gas Extraction design where others had failed. 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